Smokeless tobacco impacts oral microbiota in a Syrian Golden hamster cheek pouch carcinogenesis model

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Carcinogenesis in the Hamster Cheek Pouch

Pouches from three experimental and one control animal were excised for analysis at various times during the first week and thereafter each week of carcinogen application (9,10-dimethyl-l ,~-benzanthracene) until the 131h week, at which time large tumors were present in all remaining aninmls. IIistologic progression from normal through inflanmmtion, uniform hyperplasia, localized premalignant h...

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Spontaneous differentiated squamous cell carcinoma of cheek pouch in a Syrian hamster

A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...

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The carcinogens 9,10-dime thy 1-1,2-benzanthracene, 20-methylcholanthrene, 3,4benzpyrene, 1,2,5,6-dibenzanthracene, 1,2-benzanthracene, and 2-anthramine have been tested topically in the Syrian golden hamster. The mouse skin tumor-promoting agents, croton oil and polyoxyethylene sorbitan monostearate (Tween 60), have been tested on hamster skin following a single applica tion of 9,10-dimethyl-l...

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17rethan in the drinking water (0.~2-0.4 per cent) was administered to 5to 7-weekold Syrian golden hamsters and continued for 4~ weeks with an 8-week interval between the 40th and 48th week. This t rea tment has been found to give rise to melanotic tumors of the skin, papillomas and carcinomas of the forestomach, adenomatous polyps of the cecum, pulmonary adenomatosis, m a m m a r y tumors, hep...

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Studies of Skin Carcinogenesis in the Syrian Golden Hamster*

The carcinogens 9,10-dime thy 1-1,2-benzanthracene, 20-methylcholanthrene, 3,4benzpyrene, 1,2,5,6-dibenzanthracene, 1,2-benzanthracene, and 2-anthramine have been tested topically in the Syrian golden hamster. The mouse skin tumor-promoting agents, croton oil and polyoxyethylene sorbitan monostearate (Tween 60), have been tested on hamster skin following a single applica tion of 9,10-dimethyl-l...

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ژورنال

عنوان ژورنال: Anaerobe

سال: 2018

ISSN: 1075-9964

DOI: 10.1016/j.anaerobe.2018.05.010